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IROPAL (Iron Protein succinylate) Syrup

DRUG CATEGORY: Plain iron/ Anti-anemic

MECHANISM OF ACTION: IROPAL is a proprietary medicinal product in which the iron is bound to milk’s succinylated protein to form an iron protein complex. It is highly soluble in water. The preparation is not digested by the pepsin while it is hydrolyzed by the pancreatin at neutral pH. The iron contained in IROPAL is protected by the proteic shell from the actions of the hydrochloric acid and pepsin of the gastric juice, as a result, it does not cause gastric mucosal damage, which is common to the most of iron salts, especially those in ferrous form.The delivery of iron from IROPAL occurs in the duodenal lumen and in the jejunum as a consequence of the normal pH rise, which makes the compound soluble again and allows the digestion of the proteic shell by the pancreatic enzymes. The iron becomes so available for the physiological absorption without reaching too high peaks; an excellent absorption and the storage in the sites of the body is, gradually reached. Therefore, IROPAL does not generally cause gastrointestinal intolerance.

INDICATIONS: IROPAL (Iron protein succinylate) is used for treatment of iron deficiency anemia, latent or clear iron deficiency anemias due to insufficient intake of iron or impaired absorption, acute or chronic blood loss or infections in patients of all ages, during pregnancy and breast-feeding.

DOSAGE AND ADMINISTRATION:

Adults: 15 to 30ml (Equivalent to 40-80mg of elemental iron) in one or two administrations, preferably before meal.

Children:4mg/kg/day (Equivalent to 4mg/kg/day of elemental iron in one or two administrations, preferably before meals.

PRESENTATION: IROPAL Syrup is available in glass bottle of 60ml & 120ml (800mg eq. 40mg /15ml elemental iron)

 

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