EFELIDE (Clarithromycin) 125mg/5ml Suspension 60ml

DRUG CATEGORY: Macrolide

MECHANISM OF ACTION: Macrolides inhibits RNA-dependent protein synthesis by reversibly binding to the 50s ribosomal subunits of susceptible microorganisms. They induce dissociation of peptidyl transfer RNA (tRNA) from the ribosome during the elongation phase. Thus, RNA-dependent protein synthesis is suppressed, and bacterial growth is inhibited. Macrolides are mainly bacteriostatic but can be bactericidal depending on bacterial sensitivity and antibiotic concentration.

INDICATIONS: Respiratory tract infections including bronchitis, pneumonia, tonsillitis, sinusitis and pharyngitis. Skin and soft tissue infections such as folliculitis, cellulitis and erysipelas. Disseminated or localized mycobacterial infections due to Mycobacterium avium or Mycobacterium intracellulare. Localized infections due to Mycobacterium chelonae, Mycobacterium fortuitum, or Mycobacterium kansasii. Duodenal ulcer. Clarithromycin in the presence of acid suppression is indicated for the treatment of duodenal ulcer and in reducing the rate of ulcer recurrence

DOSAGE AND ADMINISTRATION: Adults: Clarithromycin suspensions may be used as an alternative dosage form for those adults that prefer a liquid medicine. Children 7.5 mg/kg b.i.d. up to a maximum dose of 500 mg b.i.d. The usual duration of treatment is for 5 to 10 days

PRESENTATION: Efelide Suspenion is present in plastic bottle of 60ml (125mg/5ml)