TRUTIL(Esomeprazole) 40mg Capsules

Drug Category Proton Pump Inhibitor (PPI)

MECHANISM OF ACTION Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H⁺/K⁺-ATPase in the gastric parietal cell. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

INDICATIONS Treatment of Gastroesophageal Reflex Disease (GERD). Healing of Erosive Esophagitis. maintenance of Healing of Erosive oesophagitis. Symptomatic Gastroesophageal Reflex Disease. H. pylori Eradication to Reduce the Risk. of Duodenal Ulcer Recurrence.

DOSAGE AND ADMINISTRATION 40 mg once daily for 4 to 8 weeks. Maintenance of healing of erosive esophagitis 20 mg once daily. For symptomatic reflex disease 20 mg once daily for 4 weeks. H.pylori eradication to reduce risk of duodenal ulcer 40 mg daily for 10 days along with Amoxicillin 1000 mg twice daily for 10 days & Clarithrormycin 500 mg twice daily for 10 days

Presentation 40mg  capsules are available in alu-alu pack of 2×7’s.

Myosoft Capsules (Thiocochicoside 4mg)

Drug Category: Muscle Relaxant

MECHANISM OF ACTION: Myosoft binds to GABA-A and strychnine sensitive glycine receptors. Mysoft acting as a GABA-A receptor anatagonist, its myorelaxant effects could be exerted at the supra spinal level via complex regulatory mechanisms. Although a glycinergic mechanism of action cannot be excluded.

INDICATIONS: Treatment of the painful muscular contractures in acute and chronic rhemumatologic and orthopedic diseases (lumbago, Sciatica, Cervicobrachial pain, torticollis, periarthropathy, tendinopathy)or in traumatology.

DOSAGE AND ADMINISTRATION: Two 4mg Capsules BID for 5-7 days.

PRESENTATION: Myosoft Capsules are available in the pack size of 4×5’s ALU ALU Blister pack.

ULCOFIN Suspension

Drug Category H-2 Receptor Blocker

MECHANISM OF ACTION Famotidine binds competitively to H₂-receptors located on the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released.

INDICATIONS Gastric ulcers, Duodenal ulcers, Reflux oesophagitis, Chronic episodic dyspepsia and other pathological hypersecretory states e.g., Zollinger-Ellison Syndrome. ULCOFIN Suspension is indicated for the relief of heart burn /acid indigestion and prevention of these symptoms caused by acid related diseases.

DOSAGE AND ADMINISTRATION Benign gastric & duodenal ulcers: 40mg one tablet at night for 4-8 weeks, maintenance therapy is 20mg one tablet once daily. GERD: 20mg to 40mg one tablet twice daily for 6-12 weeks, Zollinger-Ellison syndrome: Initially 20mg one tablet 6 hourly. ULCOFIN Suspension: Bening gastric & duodenal ulcers: 4 teaspoonful at night for 4-8 weeks, maintenance therapy is 2 teaspoonfuls once daily. GERD: 2 to 4 teaspoonfuls twice daily for 6-12 weeks. Zollinger-Ellison syndrome: 2 teaspoonfuls 6 hourly

Presentation Ulcofin suspension is available in the glass bottle of 120ml

ULCOFIN (Famotidine) 40mg Tablets

DRUG CATEGORY: H-2 Receptor Blocker

MECHANISM OF ACTION Famotidine binds competitively to H₂-receptors located on the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released.

INDICATIONS Gastric ulcers, Duodenal ulcers, Reflux oesophagitis, Chronic episodic dyspepsia and other pathological hypersecretory states e.g., Zollinger-Ellison Syndrome. ULCOFIN Suspension is indicated for the relief of heart burn /acid indigestion and prevention of these symptoms caused by acid related diseases.

DOSAGE AND ADMINISTRATION Benign gastric & duodenal ulcers: 40mg one tablet at night for 4-8 weeks, maintenance therapy is 20mg one tablet once daily. GERD: 20mg to 40mg one tablet twice daily for 6-12 weeks, Zollinger-Ellison syndrome: Initially 20mg one tablet 6 hourly. ULCOFIN Suspension: Bening gastric & duodenal ulcers: 4 teaspoonful at night for 4-8 weeks, maintenance therapy is 2 teaspoonfuls once daily. GERD: 2 to 4 teaspoonfuls twice daily for 6-12 weeks. Zollinger-Ellison syndrome: 2 teaspoonfuls 6 hourly

Presentation Ulcofin 20mg Tabs. are available in blister pack of 1×10’s

ULCOFIN (Famotidine) 20mg Tablets

DRUG CATEGORY H-2 Receptor Blocker

MECHANISM OF ACTION Famotidine binds competitively to H₂-receptors located on the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released.

INDICATIONS Gastric ulcers, Duodenal ulcers, Reflux oesophagitis, Chronic episodic dyspepsia and other pathological hypersecretory states e.g., Zollinger-Ellison Syndrome. ULCOFIN Suspension is indicated for the relief of heart burn /acid indigestion and prevention of these symptoms caused by acid related diseases.

DOSAGE AND ADMINISTRATION Benign gastric & duodenal ulcers: 40mg one tablet at night for 4-8 weeks, maintenance therapy is 20mg one tablet once daily. GERD: 20mg to 40mg one tablet twice daily for 6-12 weeks, Zollinger-Ellison syndrome: Initially 20mg one tablet 6 hourly. ULCOFIN Suspension: Bening gastric & duodenal ulcers: 4 teaspoonful at night for 4-8 weeks, maintenance therapy is 2 teaspoonfuls once daily. GERD: 2 to 4 teaspoonfuls twice daily for 6-12 weeks. Zollinger-Ellison syndrome: 2 teaspoonfuls 6 hourly

Presentation Ulcofin 20mg Tabs. are available in blister pack of 2×10’s

DRUG CATEGORY: Proton Pump Inhibitor (PPI)

MECHANISM OF ACTION Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H⁺/K⁺-ATPase in the gastric parietal cell. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

INDICATIONS Treatment of Gastroesophageal Reflex Disease (GERD). Healing of Erosive Esophagitis. maintenance of Healing of Erosive oesophagitis. Symptomatic Gastroesophageal Reflex Disease. H. pylori Eradication to Reduce the Risk. of Duodenal Ulcer Recurrence.

DOSAGE AND ADMINISTRATION 40 mg once daily for 4 to 8 weeks. Maintenance of healing of erosive esophagitis 20 mg once daily. For symptomatic reflex disease 20 mg once daily for 4 weeks. H.pylori eradication to reduce risk of duodenal ulcer 40 mg daily for 10 days along with Amoxicillin 1000 mg twice daily for 10 days & Clarithrormycin 500 mg twice daily for 10 days

Presentation  20mg capsules are available in alu-alu pack of 2×7’s.

ONLEZOLE (Fluconazole) 150mg Capsules

DRUG CATEGORY: Antifungal

MECHANISM OF ACTION Fluconazole is a highly selective inhibitor of fungal cytochrome P450 dependent enzyme lanosterol 14-α-demethylase. This enzyme functions to convert lanosterol to ergosterol. The subsequent loss of normal sterols correlates with the accumulation of 14-α-methyl sterols in fungi and may be responsible for the fungistatic activity of fluconazole.

INDICATIONS Candidiasis , Tinea corporis, tinea cruris or tinea pedis, Onychomycosis, Cryptococcal meningitis , Coccidioidomycosis, Cryptococcosis, Histoplasmosis, Prophylaxis of candidiasis in immunocompromised people.

DOSAGE AND ADMINISTRATION For Vaginal candidiasis and Candidal balanitis 150mg as a single oral dose. For Tinea pedis, corporis, cruris and candida infections, the recommended dosage is 150mg once weekly. Duration of Treatment: 2 to 4 weeks but tinea pedis may require treatment upto 6 weeks. For Tinea Versicolor; 300mg once weekly for 2 weeks, For tinea unguium, the recommended dosage is 150mg once weekly. Treatment of fingernail and toenail normally requires, 3 to 6 months and 6 to 12 months respectively.

Presentation Onlezole 150mg Caps. is present in Alu-Alu Blister pack of 1×1’s Caps.

MECHANISM OF ACTION: Fluconazole is a highly selective inhibitor of fungal cytochrome P450 dependent enzyme lanosterol 14-α-demethylase. This enzyme functions to convert lanosterol to ergosterol. The subsequent loss of normal sterols correlates with the accumulation of 14-α-methyl sterols in fungi and may be responsible for the fungistatic activity of fluconazole.

INDICATIONS: Candidiasis , Tinea corporis, tinea cruris or tinea pedis, Onychomycosis, Cryptococcal meningitis , Coccidioidomycosis, Cryptococcosis, Histoplasmosis, Prophylaxis of candidiasis in immunocompromised people.

DOSAGE AND ADMINISTRATION:For Vaginal candidiasis and Candidal balanitis 150mg as a single oral dose. For Tinea pedis, corporis, cruris and candida infections, the recommended dosage is 150mg once weekly. Duration of Treatment: 2 to 4 weeks but tinea pedis may require treatment upto 6 weeks. For Tinea Versicolor; 300mg once weekly for 2 weeks, For tinea unguium, the recommended dosage is 150mg once weekly. Treatment of fingernail and toenail normally requires, 3 to 6 months and 6 to 12 months respectively.

PRESENTATION: Onlezole 50mg Caps. is present in Alu-Alu Blister pack of 1×7’s Caps.

MIZOLE (Clotrimazole) 500mg Tablets

DRUG CATEGORY:  Antifungal

MECHANISM OF ACTION: Clotrimazole alters the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. This leads eventually to the cell’s death.

INDICATIONS: Vaginal Candidiasis, Trichomoniasis,Chronic Recurrent Mycosis ,Vaginitis Due to Fungi,Infectious Leucorrhoea,Vaginal Mycosis During Pregnancy, Prophylactic Against Neonatal Thrush As Prenatal Therapy

DOSAGE AND ADMINISTRATION: Only one dose of Mizole provides excellent results in vaginitis.. Treatment with Mizole should be adjusted to avoid the menstrual period and should be finished before the start of fresh menstrual cycle. If necessary a second time treatment can be repeated with Mizole tablets.

PRESENTATION: Mizole (Clotrimazole U.S.P 0.5 gm) is supplied in a box of a single tablet with applicator and a pair of packed disposable gloves

MUCORID SYRUP

DRUG CATEGORY:Mucolytic / Bronchodilator

MECHANISM OF ACTION:

Ambroxol: Ambroxol is a clinically proven systemically active mucolytic agent. When administered orally onset of action occurs after about 30 minutes. The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscous and therefore more easily removed by coughing.

Salbutamol :  is a short-acting β₂-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease.

Guaifenesin: An expectorant which clears chest congestion by loosening and reducing the viscosity of phlegm, & increasing the volume of phlegm making it easier to cough out through your mouth.

Menthol: An organic compound made synthetically or obtained from peppermint or other mint oils. It has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation.

INDICATIONS: Mucorid is indicated for clinical relief of cough associated with bronchitis, bronchial asthma, emphysema and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist.

DOSAGE AND ADMINISTRATION:

• Adults & children over 12 years: 2 teaspoonful 3 times daily
• Children 6-12 years: 2 teaspoonful 2-3 times daily
• Children 2-6 years: 1 teaspoonful 3 times daily
• Children 1-2 years: ½ – 1 teaspoonful 2 times daily

PRESENTATION: Mucorid Syrup is available in bottle of 120ml.